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Is Discontinued By Manufacturer : No
Product Dimensions : 2.88 x 2.88 x 3 inches; 4.02 ounces
Item model number : B-210-13-4oz
Date First Available : June 20, 2013
Manufacturer : Biomax Health Products Inc.
ASIN : B00DI7U88G
Best Sellers Rank: #1,014 in Health & Household (See Top 100 in Health & Household) #1 in Joint & Muscle Pain Relief Rubs
Customer Reviews: 4.2 4.2 out of 5 stars (96,915) var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
Trusted Daily Relief for Back, Neck, Knee, Shoulder & Hand Discomfort – Non-NSAID Formula. Penetrex provides targeted support for common problem areas including lower back, stiff neck, achy knees, shoulder tension, and hand soreness. Formulated without NSAIDs (non-steroidal anti-inflammatory drugs) for those seeking natural alternatives to oral medications or medicated patches for routine joint and muscle strain.
Professional-Grade Ingredients: Arnica, MSM, Vitamin B6 & Boswellia for Enhanced Support. Enhanced with clinically-studied botanicals and nutrients recognized for their soothing properties. Arnica montana has been used traditionally for centuries, while MSM (Methylsulfonylmethane), Vitamin B6, and Boswellia Serrata work synergistically to support muscles and joints experiencing occasional discomfort from exercise, repetitive motion, or daily activity.
Fast-Absorbing, Non-Greasy Cream – No Menthol Smell, Won’t Stain Clothing. Lightweight, fast-penetrating formula absorbs quickly into skin without leaving oily residue, sticky feeling, or transferring to clothes or bed sheets. Unlike menthol-based products with strong medicinal odors, Penetrex is fragrance-free with no overpowering scent, making it ideal for use anytime – at work, before bed, or during your daily routine.
Ideal for Active Adults, Athletes & Those Managing Chronic Tension – Safe for Long-Term Use. Perfect for fitness enthusiasts dealing with post-workout soreness, office workers with repetitive strain, aging adults experiencing stiffness, or anyone managing ongoing discomfort in joints and muscles. Gentle enough for consistent daily application without the concerns associated with prolonged NSAID use.
Trusted by Over 2 Million Users and Made in USA with Quality Standards You Can Count On. With a loyal customer base spanning over a decade, Penetrex has become a household name for natural topical support. Manufactured in the USA following strict quality standards, and suitable for those seeking vegan-friendly, paraben-free formulations.

Duke Tang –
Penetrex works by keeping your pain at bay so YOU can find and fix the underlying problems
Let’s get something straight from the get-go; Penetrex is a pain reliever (even said so on the label) and as a pain reliever, it works surprisingly well. However, many customer placed too much faith in the creme as a “cure-all” for their disorders/diseases/pain (basing on the 3 stars reviews and lower). In my perspective, Penetrex works by keeping your pain at bay so YOU can find and fix the underlying problems.And there lies the problem. There is a major emphasis on the YOU part.Now to paint my scenario.I was diagnosed with Patellofemoral Syndrome by two different clinics. The pain became so unbearable that I was limited to upper body exercises for three whole months. Usually in these cases, icing and rest would be prescribed, and since X-rays and MRI both showed no signs of abnormalities, ice and rest seemed like the only logical solution. I too was under the impression that my knee would recover in time but as the clock ticked, long car rides and extensive sittings became more and more unbearable. After 3 months of doing nothing, I took it upon myself to find a solution and after extensive reading and tinkering and soul searching, it seems my vastus medialis (inner quadriceps muscle) was at fault. This “little fault” caused a myriad of messes: My lateralis tightened up, I always felt a tug in my right hip flexor, and because of the tug, my t-spine (I’m a nerd, I know) would prematurely round when I squat. EMG results confirmed my hypothesis; my VMO would shut down as soon as I ventured beyond parallel during any sort of exercises. Now that I am armed with this discovery, I was ready to make drastic changes. The only drawback was the massive, excruciating pain that accompanied rehab and therapy work, even the lightest workload, such as bodyweight squat and peterson step-up.That’s when I discovered Penetrex. The creme allowed me to progressively strengthen my VMO, without having to endure the torment.Here is another scenario: My friend who is currently suffering from a similar knee issue. His VMO rides even higher than mine, almost 4 inches above the kneecap. He is a long distance runner and I am a powerlifter. Two people from two different sports, suffering from the same problem. After convincing him to drop running for a while (athletes can be very hard-headed) and go through an extensive rehab program, his kneecap no longer slides and I bet with a little more time, the pain will disappear altogether.Yes, I do wholeheartedly recommend Penetrex for all acute injuries (and some chronic). I came to realize that there are a certain few customers who view Penetrex as nothing more than a glorified DMSO product, and to a certain extent, I agree with them. However, that is not necessarily a bad thing! Pure DMSO is extremely potent and works well to ease tendinitis and other symptoms. I myself have used DMSO but found that with multiple applications in a day, even with less potent concentration and/or mixes, it tends to eat away the skin fairly fast. Penetrex does not do this and eventually you have to ramp up the dosage (while doing rehab work, of course) to speed up the healing process.Whether it is straight DMSO or Penetrex, like I said, YOU will have to play a huge part in the recovery stage. Do not expect to dabble on the creme and by some miracle, your tendinitis will dissipate. If you play golf and suffer from elbow and back pain, common sense would dictate that you take some time off and REALLY find that kink in your kinetic chain. Common sense also tells us that golfing is a very one-sided sport, so wouldn’t it make sense to focus on a bit of weight training to strength the oblique/back muscles and biceps/triceps? If you’re a long distance runner and are suffering from knee pain, don’t continue grinding your knees to dust! Stop running and find the underlying problem! Take up weightlifting to strengthen the entire posterior chain; more muscle = less force absorption on the knees when the feet hit the ground. And judging from the numerous runners who are diagnosed with some kind of patella problem, the VMO is at fault.This review should not be viewed as me chastising or as a lecture but as me sharing one of my humble life experiences 🙂 We all have to do things that we hate and being a strength athlete who absolutely loved to squat, it was heartbreaking and a blow to my ego when I was reduced to doing peterson step-ups and body weight lunges. If you truly love what you do, be it golfing, running, lifting, or playing competitive sports, then do everything in your power to make sure you can continuing doing what you’re doing!
I love it! –
It really works. Must have
I don’t write reviews that often but I have to for this. It’s amazing. It’s fast acting. Instant relief. No cooling sensation slight menthol scent but not over whelming. I will be buying this again as soon as I’m out. So happy I found something that actually works for my knee pain and stiffness.
Stephen seagal –
Effective
Actually works. I give it a 4/5 for effectiveness. It was effective, short term, in treating my tendinitis. Anecdotally reduced my pain by 50-80% while doing sports. Lasts for an hour, or two. I would advise getting the roll on version, but either work.The price is a 3/5.If you need a short term relief in pain it’s worth a shot.
Mike –
It worked so well, we ordered the 8oz. pump so she can refill the small one for travel.
Bought this for my girlfriend who has back problems. L1-L5. Got the 2oz. size in case she didn’t like it.She had been using other homeopathic type relief creams with some success. This one seems to last at least as long but has a slightly better level of pain relief for her. Everyone is different, but I would recommend giving this a shot.It worked so well, we ordered the 8oz. pump so she has one at home and can refill the small one for travel. It’s not greasy, absorbs well. We ordered the roll-on variety to see if it is better or just a different.
Maya S. –
Does This Thing Really Work?
I have suffered from Runner’s Knee (aka patellofemoral pain syndrome) for over 10 years. I don’t have the pain all the time, but when it occurs it’s usually only when walking or running. Typically the pain subsides on its own after a few hours of rest. But about a week ago I went on an 8-mile hike that completely messed up my right knee and I was out of commission for 4 days. I had no choice but to rest, ice, take ibuprofen, and compress during that time. I was desperate to alleviate the pain so I could resume normal activity. So I thought I would add Penetrex to my self-care routine.Penetrex is a cutaneous anti-inflammatory medication that is delivered through the skin. What appealed me to this specific brand was that it didn’t appear to be pain masking like other brands. While heat and cold definitely dulls the sensation of pain, it can be dangerous in that it can give the illusion the problem is solved. So you may feel ready to resume activity and unknowingly make the injury worse. Penetrex doesn’t do that. There is no heat, icy feeling, or numbness that occurs.I have tried both the cream and the roll-on and honestly I don’t find much difference between the two in terms of efficacy. Typically, cutaneous (skin) medications are best delivered using a cream base. More often than not when you are prescribed a topical medication from your doctor or dermatologist, it is in a cream or ointment form. They don’t evaporate as quickly and are more effective at delivering the medication.This roll-on is not a cream, but a clear serum-like liquid. It’s definitely more convenient than the cream as you can just roll it on without getting it on your hands. It also dries much faster. Even after rubbing the cream into my skin for a while, the area remains somewhat tacky for about 15 to 20 minutes. The roll-on formula is dry within 2 to 3 minutes. But roll-ons are less hygenic than using a cream with a clean spatula (every time you roll all those dead skin cells start mixing with the ball and liquid), but the quick evaporation makes me wonder if the ingredients are able to penetrate the skin as well as the cream. I also find that the cream lasts longer as I can use less.But ultimately, does Penetrex really work? Or is it just an effective placebo? I can’t really say for sure and that makes it hard for me to establish a fair rating (hence putting it somewhere in the middle). To be fair, I didn’t see Runner’s Knee as an issue this product claims to treat, so it could just be that it’s not meant for that. I did feel like the pain did subside about a half hour after applying it, but the effects were temporary lasting only a few hours. I definitely had to apply it 3-4 times a day per the directions.Even so, it’s hard to say if this cream is what actually relieved my pain as there were other variables to consider. I also iced my knee regularly, added compression, and kept off my feet during recovery. In all it took a full week for the pain to completely go away, and given the other methods I used it may have taken the same amount of time even without this cream.In conclusion, I’m not here to say that this cream doesn’t work. It may work better for the conditions it actually claims to treat. But it certainly didn’t perform any miracles on my knee. I want to be fair about this product though, and if I end up having some other type of pain I will certainly give both the cream and this roll-on another try. If it works, I’ll update my review and the star rating.
Marie S. from Philly –
This truy does help with joint pain
It’s a five-star purchase. Very easy to apply, very easy to rub gently in to soothe aching joints and muscles. When artiritis pain wakes me up, I grab Penetrex and almost before I know it, I am peacefully asleep again. I like that there is no smell, and it doesnt’ feel too thick or greasy at all. It’s a nice white color and as for value – the price is fair, all things considered. My belief is that if a product really does work, then it is worth the price. Very happy with it and will re-order when it runs out.
Cleopatra J. –
Excelente Servicio Amable llego antes de lo previsto buena calidad le encantó ya que le ayudo mucho a sus dolores articulares
Beza. G –
Good
Sajid patel –
My wife backpain fully curred
Bob J. –
Not bad as a pain relieving cream, but far too expensive for me.
Leila –
تخفف من الالام الخفيفة